If you have recently been diagnosed with colorectal cancer, your doctor will have discussed your treatment options with you. Each cancer is different in every single person, meaning that there is no one size fits all approach to treatment.
A very common treatment process involves surgery to remove the tumour, followed by a cycle of chemotherapy to make sure that all cancerous cells have been destroyed. In some cases, surgery is sufficient to completely remove the cancer and chemotherapy is unnecessary. In some cases chemotherapy is essential. Your clinician will make this decision based on the information available to them. Decision making can be improved with additional information. Helping your doctor be more informed about your cancer may help avoid unnecessary chemotherapy and the side-effects that often accompany treatment.
Our suite of digital tests have been created to help your doctors make the most informed decisions on your treatment plan, including whether or not chemotherapy is needed.
Our tests work by utilising genetic information taken from your DNA, which is collected through a blood sample, mouth swab or from the piece of tumour removed during the surgical resection, this allows doctors to create a personalised treatment plan based on your results. Your doctor will use these test results alongside other information to make an informed decision on how best to treat you.
20-30% of colorectal cancer patients experience severe drug side effects when treated with the most common chemotherapy drug – 5FU (or capecitabine). The ToxNav test identifies if you are at high risk of these side effects before you’re treated. So your clinicians can prescribe safer chemotherapy drug doses, and reduce the likelihood of toxicity. ToxNav also identifies if you are in the small subset of patients (1% of all patients) that should avoid 5FU based chemotherapy altogether due to high risk of life-threatening toxicities.
This test is carried out after colorectal cancer surgery to identify if you are at Low Risk, intermediate Risk or High Risk of relapse. This will allow surgeons and oncologists to personalise your treatment to you, potentially avoiding chemotherapy if you have a high likelihood of cure by surgery alone.
Currently in development, ColoPredict can identify if you are at increased risk of developing colorectal cancer with only a simple mouth swab. If you are found to be at higher risk, doctors can recommend steps to minimise your risk of colorectal cancer including exercise, healthy eating, early screenings and colonoscopies.